Prozac (Fluoxetine): A Guide for Anxiety Treatment

Prozac (fluoxetine) was the first SSRI to hit the market and remains one of the most commonly prescribed antidepressants. At Next Step Psychiatry in Lilburn, we help patients understand how this medication might help with anxiety disorders.

How Prozac Works

Prozac is a selective serotonin reuptake inhibitor (SSRI). It blocks the reabsorption of serotonin in your brain, making more available to regulate mood and anxiety. It may also promote neuroplasticity—your brain's ability to form new connections.

FDA-Approved Uses

• Major depressive disorder
• Panic disorder
• OCD
• Bulimia nervosa

It's also commonly used off-label for generalized anxiety, PTSD, social anxiety, and PMDD.

Advantages of Prozac

• Long half-life: Prozac stays in your system longer than other SSRIs, making missed doses less problematic and withdrawal symptoms milder
• Well-studied: Decades of research support its safety and efficacy
• Available as generic: Cost-effective option

Common Side Effects

• Nausea
• Insomnia or drowsiness
• Headache
• Nervousness (may improve over time)
• Sexual dysfunction
• Weight changes

How Long Until It Works?

Initial improvement may appear in 1-2 weeks, but full effects typically take 4-6 weeks. Don't give up too early.