Depression and Weight: Understanding the Physical Connection

Depression is far more than feeling sad. It affects your whole body, including appetite and weight. Some people lose weight with depression, while others gain it. Understanding this connection helps you recognize symptoms and seek appropriate care.

Why Depression Can Cause Weight Loss

• Decreased appetite: Loss of interest in food is a common depression symptom
• GI symptoms: The gut-brain connection means depression can cause nausea and stomach upset
• Hormonal changes: Depression affects hunger-regulating hormones
• Increased inflammation: Can disrupt appetite regulation
• Medication side effects: Some antidepressants decrease appetite

Why Depression Can Cause Weight Gain

• Increased appetite: Especially common in atypical depression
• Emotional eating: Using food for comfort
• Decreased activity: Fatigue and low motivation reduce physical activity
• Medication side effects: Some antidepressants increase appetite

Other Physical Symptoms of Depression

• Persistent fatigue
• Sleep disturbances
• Unexplained aches and pains
• Headaches
• Digestive problems

When to Seek Help

If you're experiencing persistent sadness, hopelessness, loss of interest in activities, and changes in weight or appetite for more than two weeks, it's time to reach out for professional help. Treatment can address both mental and physical symptoms.