Depakote for Bipolar Disorder: What Atlanta-Area Patients Should Know

If you've been diagnosed with bipolar disorder, medication is often essential for managing mood episodes. Depakote (divalproex sodium) is a commonly prescribed mood stabilizer that can help level out the highs and lows. Here's what our Gwinnett County patients frequently ask about this medication.

What Is Depakote?

Depakote is an antiseizure medication that's FDA-approved for treating manic and mixed episodes in bipolar disorder, as well as preventing migraines and treating epilepsy. It works by increasing GABA levels in the brain, which produces calming effects that help reduce manic symptoms.

How It Works for Bipolar

Depakote is particularly effective for manic and mixed episodes but less so for bipolar depression. Many patients take a second medication to address depressive symptoms. When Depakote is working, you'll feel more level and stabilized—mood at a neutral baseline rather than swinging between extremes.

Common Side Effects

• Drowsiness
• Nausea or stomach upset
• Weight changes
• Hair thinning
• Tremors
• Dizziness

Important Considerations

Pregnancy: Depakote is not recommended for pregnant women or those planning pregnancy due to risks of birth defects. Women of childbearing age should discuss alternative options.

Liver function: Regular blood tests may be needed to monitor liver function and medication levels.